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Updated: May 9, 2026

Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae
09:05

Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae

Published on: April 18, 2016

脱基因酶在从ER中退化的膜蛋白降解过程中加剧了基质歧视

Zai-Rong Zhang1, Juan S Bonifacino, Ramanujan S Hegde

  • 1Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 18 Library Drive, Bethesda, MD 20892, USA. zairong.zhang@gmail.com

Cell
|July 30, 2013
PubMed
概括

乌比基连酶控制蛋白质命运,但微妙的相互作用如何决定结果仍然不清楚. 这项研究揭示了连续的二维基因化放大了蛋白质-酶结合的微小差异,确保了精确的膜蛋白质质量控制.

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