在 Nd ((3+) 敏感的核心外纳米粒子中对光子向上转换的机械研究
Xiaoji Xie1, Nengyue Gao, Renren Deng
1Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.
Journal of the American Chemical Society
|August 17, 2013
概括
研究人员使用 (Nd3+) 离子开发了新的核心外升级转换纳米粒子. 这些纳米粒子在更安全的激发波长下为生物成像提供增强的发光,最大限度地减少过热问题.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术 纳米技术
- 生物医学工程 生物医学工程
背景情况:
- 上转化纳米粒子 (UCNPs) 对于生物成像至关重要,但传统的980nm激发会导致过热.
- (Nd3+) 离子可以作为上转换过程的敏感剂.
研究的目的:
- 设计和合成使用Nd3+离子在795nm激发的新型核心外UCNP.
- 为了增强生物成像应用的上转换发光.
- 为了减轻与传统的UCNP激发相关的过热问题.
主要方法:
- 通过空间限制的 Nd3+ 离子合合成核心UCNP.
- 使用Nd3+作为兰化物激活剂 (Er3+,Tm3+,Ho3+) 的敏感剂.
- 描述UCNP属性和上转换发光效率.
主要成果:
- 成功合成了核心外UCNP,在795nm有效激发.
- Nd3+敏感化显著增强了激活器的升级转换辐射.
- 与980nm激发相比,过热问题降至最低.
- 在外层中实现了 Nd3+ (~0 mol %) 的高度兴奋剂.
结论:
- 开发的核心UCNP为生物成像提供了一个有希望的替代方案.
- 795nm激发波长是生物相容的,可以减少热损伤.
- 这些UCNP提供了明亮的发光而没有自光,非常适合敏感的生物成像.
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