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Updated: Jan 20, 2026

Correlating Gene-specific DNA Methylation Changes with Expression and Transcriptional Activity of Astrocytic KCNJ10 Kir4.1
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精确的发育基因表达源于全球随机转录活动

Shawn C Little1, Mikhail Tikhonov2,3, Thomas Gregor2,3

  • 1Department of Molecular Biology, Howard Hughes Medical Institute, Princeton University, Princeton, NJ 08544, USA.

Cell
|August 20, 2013
PubMed
概括

发育精确性来自于平均基因表达噪声. 尽管转录的波动很高 (~45%),但mRNA水平在Drosophila胚胎中的核之间仅有~8%的差异,确保了精确的模式.

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