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All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
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机械检查点通过YAP/TAZ调节,通过actin处理因子控制多细胞生长

Mariaceleste Aragona1, Tito Panciera1, Andrea Manfrin1

  • 1Department of Molecular Medicine, University of Padua School of Medicine, viale Colombo 3, 35131 Padua, Italy.

Cell
|August 20, 2013
PubMed
概括

组织结构和机械力量通过YAP/TAZ信号调节细胞增殖. 像拉伸和硬度这样的物理线索控制细胞生长,通过保持空间控制来预防癌症等疾病.

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