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一个结构化的D-RNA分子被一个L-RNA胺体所结合

Jonathan T Sczepanski1, Gerald F Joyce

  • 1Departments of Chemistry and Molecular Biology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|August 28, 2013
PubMed
概括

研究人员开发了一种新型L-RNA吸收体,该吸收体与HIV-1转激活响应 (TAR) RNA的D形式结合. 这种结合抑制了一个关键复合体,这表明L-aptamers是结构RNA的潜在治疗方法.

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