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Updated: May 8, 2026

Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay
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Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay

Published on: November 11, 2018

对于GATM表达的他类药物依赖的QTL与他类药物诱导的肌病相关

Lara M Mangravite1, Barbara E Engelhardt, Marisa W Medina

  • 1Sage Bionetworks, 1100 Fairview Avenue North, Seattle, Washington 98109, USA. lara.mangravite@sagebase.org

Nature
|September 3, 2013
PubMed
概括

达类药物降低胆固醇,但可能导致肌肉病变. 发现了一种涉及GATM基因的遗传联系,这可能解释了他类药物诱导的肌肉损伤,并提供了新的治疗点.

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