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氧化Ca(2+) /卡尔莫杜林依赖的蛋白激酶II触发了心房动

Anil Purohit1, Adam G Rokita, Xiaoqun Guan

  • 1Department of Internal Medicine, Division of Cardiovascular Medicine and Cardiovascular Research Center, Carver College of Medicine (A.P., A.G.R., X.G., B.C., O.M.K., Z.G., E.D.L., H.S., A.C.B., R.N.E.-A., P.D.S., R.M.W., L.-S.S., M.E.A.), Department of Obstetrics and Gynecology (B.Y.), and Department of Molecular Physiology and Biophysics (M.E.A.), University of Iowa, Iowa City; Institute of Pharmacology, Faculty of Medicine, University Duisburg-Essen, Essen, Germany, and Division of Experimental Cardiology, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany (N.V., D.D.); Cardiology and Pneumology, German Heart Center, University Hospital Goettingen, Goettingen, Germany (S.N., T.S., L.S.M.); and Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX (N.L., X.H.T.W.).

Circulation
|September 14, 2013
PubMed
概括

氧化Ca2+/卡尔莫杜林依赖蛋白激酶II (CaMKII) 与心房 (AF) 有关. 减少氧化CaMKII可能为AF患者提供新的治疗方法.

关键词:
ангиотензин II 的使用心律失常,心脏节律失常,心脏病.心房动是心房动的一种.类型II的依赖-芽素蛋白蛋白激酶.有活性氧物种的反应性氧物种.

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