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纳诺格,Pou5f1和SoxB1在母体转化为胚胎的过程中激活了胚胎的基因表达

Miler T Lee1, Ashley R Bonneau, Carter M Takacs

  • 11] Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06510, USA [2].

Nature
|September 24, 2013
PubMed
概括

母性纳诺格,Pou5f1 (Oct4) 和SoxB1转录因子启动斑马鱼的细胞体基因组激活 (ZGA). 它们的缺失阻碍了发育,并阻止了关键基因的激活,包括miR-430,这对于母体到卵巢过渡 (MZT) 至关重要.

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