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乙2上腺素受体的上腺素激活结构被一个工程纳米体稳定

Aaron M Ring1,2, Aashish Manglik1, Andrew C Kruse1

  • 1Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305, USA.

Nature
|September 24, 2013
PubMed
概括

研究人员捕获了与上腺素结合的β-2上腺受体 (β2AR) 的活性状态. 这一突破揭示了G-蛋白合受体 (GPCRs) 尽管具有不同的连接体亲和力,但仍然保留了激活机制.

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