蔓越产品和预防尿路感染
Ruth Jepson1, Jonathan Craig, Gabrielle Williams
1Centre for Population Health Sciences, Scottish Collaboration for Public Health Research and Policy, University of Edinburgh, Scotland. ruth.jepson@ed.ac.uk
JAMA
|October 3, 2013
概括
蔓越产品,包括果汁和补充剂,似乎无法预防尿路感染 (UTI). 需要进一步的研究来了解为什么临床试验显示没有关联.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 预防医学 预防医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 尿路感染 (UTI) 很常见,特别是在女性中.
- 蔓越产品已被事推用于预防尿路感染.
- 支持蔓越在预防尿路感染方面的疗效的科学证据仍然是不确定的.
研究的目的:
- 评估蔓越产品消费与预防尿路感染 (UTI) 之间的关联.
- 为了比较蔓越产品与安慰剂或其他预防尿路感染的干预措施的有效性.
主要方法:
- 对调查蔓越产品 (果汁,药片,囊,糖) 的临床试验进行系统审查和元分析.
- 使用蔓越产品与对照组的参与者中尿路感染发病率的比较.
主要成果:
- 在分析的临床试验中,没有发现蔓越产品与尿路感染的发病率降低有关.
- 没有观察到蔓越产品对尿路感染具有统计学意义的预防作用.
结论:
- 目前的临床试验数据不支持使用蔓越产品来预防尿路感染.
- 缺乏观察到的关联的潜在原因包括参与者坚持的问题,产品中的活性化合物度不足或研究中的统计能力不足.
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