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自促进了初级纤毛发育,通过将OFD1从中心卫星中移除

Zaiming Tang1, Mary Grace Lin, Timothy Richard Stowe

  • 1Center for Autophagy Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

Nature
|October 4, 2013
PubMed
概括

自会降解中心卫星的OFD1蛋白质,促进初级膜的形成. 这一过程对于正常细胞和癌细胞的纤毛发育至关重要,揭示了自在有机体生物发育中的新作用.

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