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帕内特细胞作为肠道炎症的起源地

Timon E Adolph1, Michal F Tomczak, Lukas Niederreiter

  • 11] Division of Gastroenterology and Hepatology, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK [2].

Nature
|October 4, 2013
PubMed
概括

肠上皮细胞中的自和未折叠蛋白质反应 (UPR) 途径对于预防克罗恩病至关重要. 两者的损害导致严重的乳头炎,突出显示了疾病发展中的帕内斯细胞功能障碍.

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