在亚洲人,西班牙裔,黑人和白人中发生心房动
Thomas A Dewland1, Jeffrey E Olgin, Eric Vittinghoff
1Department of Medicine, Division of Cardiology, Electrophysiology Section (T.A.D., J.E.O., G.M.M.) and the Department of Epidemiology and Biostatistics (E.V.), University of California, San Francisco, CA.
Circulation
|October 10, 2013
概括
与黑人,西班牙裔和亚洲人相比,白人与心房动 (AF) 的风险更高. 在白人中,这种增加的AF风险在缺少心血管风险因素时最为明显.
科学领域:
- 心脏病学 心脏病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 之前关于种族和心房动 (AF) 的研究主要使用二分化比较 (白人与黑人).
- 这限制了先前的研究,让人们不确定白种是否会增加AF风险,黑种是否会提供保护.
研究的目的:
- 在一个庞大而多样化的群体中,研究种族与发生性心房 (AF) 风险之间的联系.
- 为了确定白种是否与其他种族群体相比独立地与增加的AF风险有关.
- 探索心血管风险因素如何改变种族和AF之间的关系.
主要方法:
- 利用医疗保健成本和利用项目 (HCUP) 数据库用于加利福尼亚州 (2005-2009) 的医院护理.
- 在一个近1400万患者的队列中,使用Cox比例危险模型检查了事件AF.
- 在多变量分析中根据患者人口统计和确定的AF风险因素进行调整.
主要成果:
- 与白人相比,黑人,西班牙裔和亚洲人的AF风险明显较低 (HR分别为0.84,0.78和0.78).
- 白人个体在没有获得的心血管风险因素的情况下显示出不成比例地更高的AF风险.
- 白人中增加的AF风险在出现并发症的情况下减少或逆转.
结论:
- 在一个大型的住院队列中,与黑人,西班牙裔和亚洲人相比,白人与心房动 (AF) 的风险增加有关.
- 在白人中观察到的高AF风险在没有心血管并发症时最为明显.
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