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通过HOIP对线性ubiquitin链的酶特异结合的结构基础

Benjamin Stieglitz1, Rohini R Rana1, Marios G Koliopoulos1

  • 1Division of Molecular Structure, MRC-National Institute for Medical Research, The Ridgeway, London NW7 1AA, UK.

Nature
|October 22, 2013
PubMed
概括

线性ubiquitin链通过激活核因子 (NF) -κB来调节免疫力和炎症. 这是一种HOIP酶.

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