Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Modified-Release Drug Delivery Systems: Stimuli-Activated01:30

Modified-Release Drug Delivery Systems: Stimuli-Activated

184
Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also...
184
Channel Rhodopsins01:11

Channel Rhodopsins

2.5K
Most organisms use photoreceptors to sense and respond to light. Examples of photoreceptors include bacteriorhodopsins and bacteriophytochromes in some bacteria, phytochromes in plants, and rhodopsins in the photoreceptor cells of the vertebral retina. The light-sensitive property of these receptors is because of the bound chromophores, such as bilin in the phytochromes and retinal in the rhodopsins.
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
2.5K
Aquaporins01:25

Aquaporins

5.0K
Aquaporins or AQPs are a family of integral membrane proteins whose primary function is to transport water, while some called aquaglyceroporins also transport glycerol. In addition, aquaporins have also been suspected to be involved in transporting volatile substances, such as carbon dioxide and ammonia, across membranes. Such AQPs that act as gas channels are often highly expressed in cells involved in the gaseous exchange, such as red blood cells, epithelial cells, and pulmonary capillaries.
5.0K
Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

Ligand-Gated Ion Channel Receptor: Gating Mechanism

4.6K
Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
4.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Design Principles and Routes for Calcium Alkoxyaluminate Electrolytes.

The journal of physical chemistry letters·2024
Same author

Robust, Enantioselective Construction of Challenging, Biologically Relevant Tertiary Ether Stereocenters.

ACS catalysis·2023
Same author

Highly Enantioselective Catalytic Alkynylation of Quinolones: Substrate Scope, Mechanistic Studies, and Applications in the Syntheses of Chiral <i>N</i>-Heterocyclic Alkaloids and Diamines.

ACS catalysis·2023
Same author

Side-chain torsional dynamics strongly influence charge transport in organic semiconductors.

Chemical communications (Cambridge, England)·2022
Same author

Host-Guest Complexation-Mediated Supramolecular Photon Upconversion.

Journal of the American Chemical Society·2020
Same author

A diverse view of science to catalyse change.

Nature chemistry·2020

相关实验视频

Updated: May 6, 2026

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles
12:51

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

Published on: November 14, 2015

9.4K

一个水溶性pH触发的分子开关.

Sergio Grunder1, Psaras L McGrier, Adam C Whalley

  • 1Department of Chemistry, Northwestern University , 2145 Sheridan Road, Evanston, Illinois 60208-3113, United States.

Journal of the American Chemical Society
|November 9, 2013
PubMed
概括

这项研究介绍了一种可二元化的捐赠者-接受者 [2]catenane分子开关. 酸性条件选择性地将基单元放置在旋腔内,证明了受控的分子运动.

科学领域:

  • 超分子化学 超分子化学
  • 分子机器分子机器
  • 有机化学 有机化学

背景情况:

  • 捐赠者-接受者 [2]链是机械互锁的分子,在分子装置中具有潜在的应用.
  • 连链体中的二元性允许不同的结构状态,这对于分子切换功能至关重要.
  • 调查的特定基包括含基的皇冠和1,5-胺纳单元,通过四基旋机械连接.

研究的目的:

  • 在固态和溶液中研究可二相结合的捐赠体-接受体 [2]catenane 的转化异构.
  • 通过使用化学刺激,证明了catenane的同位体状态的受控切换.
  • 为了描述二衍生物,并确认基单元在旋风腔内的选择性包含.

主要方法:

  • 紫外/紫光光谱法用于监测与同位素切换相关的电子变化.
  • (1) H NMR 光谱法以阐明结构变化并确认质子化状态.
  • 捐赠体接受体 [2]catenane及其衍生物的合成和表征.

主要成果:

  • [2]catenane存在于固体和溶液状态的转化异构体的混合物中.
  • 用盐酸处理诱导一个开关,产生一个单一的二衍生物.
  • 光谱证据证实,只有基单元在二质子化状态下被封装在旋风腔内.

更多相关视频

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch
09:33

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch

Published on: February 7, 2022

3.3K
Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks
07:50

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Published on: November 25, 2015

14.1K

相关实验视频

Last Updated: May 6, 2026

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles
12:51

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

Published on: November 14, 2015

9.4K
Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch
09:33

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch

Published on: February 7, 2022

3.3K
Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks
07:50

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Published on: November 25, 2015

14.1K
  • 分子开关可以使用1,4-diazabicyclo[2.2.2]octane.重新设置.

    • 结论:

    • 研究的捐赠者-接受者 [2]catenane 功能作为可控制状态的可双性化的分子开关.
    • 选择性质子和封装证明了对相互锁定的组件相对位置的精确控制.
    • 这项工作突出了机械互锁分子在开发响应和可切换系统方面的潜力.