Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

2.6K
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
2.6K
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

1.8K
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
1.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Design, Implementation, and Advances in Indirect SERS Sensors for Biomedical and Human-Health-Related Analyte Detection.

Sensors (Basel, Switzerland)·2026
Same author

Retraction Note: Facial nerve preservation following gamma knife radiosurgery for vestibular schwannomas in neurofibromatosis type 2: a systematic review and meta-analysis of 552 tumors.

Neurosurgical review·2026
Same author

Facial nerve preservation following gamma knife radiosurgery for vestibular schwannomas in neurofibromatosis type 2: a systematic review and meta-analysis of 552 tumors.

Neurosurgical review·2026
Same author

Acoustic features of and behavioral responses to emotionally intense mouse vocalizations.

Behavioural brain research·2025
Same author

Comprehensive biobanking to enhance precision medicine in head & neck cancer through systematic sample collection & data integration.

The Indian journal of medical research·2025
Same author

Prevalence and patterns of self-medication practices in India: A systematic review and meta-analysis.

Medical journal, Armed Forces India·2025

相关实验视频

Updated: May 6, 2026

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering
09:13

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering

Published on: July 6, 2019

7.2K

通过表面增强的空间偏移拉曼光谱法透视骨.

Bhavya Sharma1, Ke Ma, Matthew R Glucksberg

  • 1Department of Chemistry and ‡Deptartment of Biomedical Engineering, Northwestern University , 2145 Sheridan Road, Evanston, Illinois 60208-3113, United States.

Journal of the American Chemical Society
|November 9, 2013
PubMed
概括
此摘要是机器生成的。

表面增强的空间偏移拉曼光谱 (SESORS) 现在可以通过骨头进行测量. 这一突破使生物样品的非侵入性成像能够实现,进步了体内诊断.

更多相关视频

Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy
13:48

Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy

Published on: May 29, 2012

20.4K
Correlative Optical Spectroscopy and Mass Spectrometry Imaging Methodology to Visualise Drug Distribution in a Soft Tissue Section
07:05

Correlative Optical Spectroscopy and Mass Spectrometry Imaging Methodology to Visualise Drug Distribution in a Soft Tissue Section

Published on: June 20, 2025

1.6K

相关实验视频

Last Updated: May 6, 2026

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering
09:13

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering

Published on: July 6, 2019

7.2K
Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy
13:48

Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy

Published on: May 29, 2012

20.4K
Correlative Optical Spectroscopy and Mass Spectrometry Imaging Methodology to Visualise Drug Distribution in a Soft Tissue Section
07:05

Correlative Optical Spectroscopy and Mass Spectrometry Imaging Methodology to Visualise Drug Distribution in a Soft Tissue Section

Published on: June 20, 2025

1.6K

科学领域:

  • 生物光子学 生物光子学
  • 频谱学是一种光谱学.
  • 生物医学成像技术 生物医学成像技术

背景情况:

  • 表面增强空间偏移拉曼光谱 (SESORS) 是一种无标签的技术,有可能用于体内成像.
  • 之前的SESORS应用仅限于皮下或嵌入式SERS基板.
  • 通过骨进行体内成像仍然是一个重大挑战.

研究的目的:

  • 为了证明SESORS通过骨头进行测量.
  • 为了评估SESORS通过骨的检测极限.
  • 探索通过骨干SESORS数据的定量分析.

主要方法:

  • 使用了涂有拉曼记者分子的SERS活性纳米粒子 (纳米标记).
  • 通过不同厚度 (3-8毫米) 的骨样本获得的SESORS光谱.
  • 采用最小平方支向量机器分析用于定量检测.

主要成果:

  • 通过3-8毫米的骨头成功获得了SESORS光谱.
  • 通过骨头检测了稀释的纳米标签样本 (~2 × 10 个粒子) 的证明.
  • 使用机器学习分析验证的定量检测能力.

结论:

  • SESORS可以有效地通过骨头进行测量,克服以前的局限性.
  • 这项技术显示了通过头骨进行神经化学物质的非侵入性,实时光谱监测的前景.
  • 透骨SESORS为需要深层组织成像的生物医学应用开辟了新的途径.