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活动依赖转录因子NPAS4调节域特异性抑制

Brenda L Bloodgood1, Nikhil Sharma, Heidi Adlman Browne

  • 11] Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Division of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA [3].

Nature
|November 9, 2013
PubMed
概括

在小鼠中,行为驱动的NPAS4表达重新安排CA1金字塔神经元上的抑制突触. 这种调节增加了体内抑制,同时减少了树突抑制,影响了神经元输出和可塑性.

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