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Updated: May 6, 2026

Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis
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林28通过重新编程细胞代谢来增强组织修复

Ng Shyh-Chang1, Hao Zhu, T Yvanka de Soysa

  • 1Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Boston, MA 02115, USA; Manton Center for Orphan Disease Research, Boston, MA 02115, USA; Howard Hughes Medical Institute, Boston, MA 02115, USA; Department of Medicine, Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.

Cell
|November 12, 2013
PubMed
概括

在成年组织中重新激活Lin28a通过增强细胞能量生产来促进再生. 这种RNA结合蛋白重编程新陈代谢以改善组织修复,为衰老和愈合提供了新的见解.

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