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Updated: May 6, 2026

Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations
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染色体连接图显示了动态促进剂-增强剂的长距离关联

Yubo Zhang1, Chee-Hong Wong1, Ramon Y Birnbaum2

  • 1Sequencing Technology Group, Joint Genome Institute, Lawrence Berkeley National Laboratory, Walnut Creek, California 94598, USA.

Nature
|November 12, 2013
PubMed
概括

这项研究绘制了小鼠干细胞中的全基因组染色质相互作用图,以了解转录调节. 它揭示了细胞类型特定的增强剂-促进剂连接,在发育过程中将染色质结构与基因表达联系起来.

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