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相关概念视频

Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

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Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
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Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

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Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
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Cancer Prevention02:59

Cancer Prevention

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Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

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The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
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Cancer02:18

Cancer

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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相关实验视频

Updated: May 6, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
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Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

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结肠直肠癌是一种癌症.

Hermann Brenner1, Matthias Kloor2, Christian Peter Pox3

  • 1Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany.

Lancet (London, England)
|November 15, 2013
PubMed
概括

结肠直肠癌每年影响超过120万人,发病率与西方生活方式有关. 早期查显著降低了结肠直肠癌的发病率和死亡率,尽管全球范围内的计划仍未得到充分利用.

科学领域:

  • 在瘤学瘤学.
  • 公共卫生 公共卫生
  • 流行病学 流行病学

背景情况:

  • 结肠直肠癌 (CRC) 是一个主要的全球健康问题,每年有超过120万个新病例和60万例死亡.
  • 癌症发病率呈现出显著的全球变化,与西方生活方式因素密切相关,在男性和老年人 (平均年龄约70岁) 中更为普遍.
  • 虽然遗传因素起作用,但大多数CRC病例是零星的,通过腺瘤-癌瘤序列随着时间的推移而发展.

研究的目的:

  • 提供关于结直肠癌流行病学,风险因素和管理的全面概述.
  • 突出生活方式对CRC发病率的影响.
  • 强调CRC查计划的重要性和当前的局限性.

主要方法:

  • 对结直肠癌发病率和死亡率的流行病学数据的审查.
  • 分析风险因素,包括年龄,性别和生活方式.
  • 目前的治疗基石的总结:手术,放射治疗和化疗.
  • 基于疾病阶段的生存率的评估.
  • 对查在减少CRC发病率和死亡率方面的有效性进行评估.

主要成果:

  • 全球CRC发病率和死亡率各不相同,与西方生活方式相关.

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Last Updated: May 6, 2026

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  • 治疗结果显示了广泛的生存率范围,从阶段I的>90%到阶段IV疾病的<10%.
  • 查显然可以减少CRC的发病率和死亡率,但有组织的查计划尚未得到广泛实施.
  • 结论:

    • 结肠直肠癌是一个重要的全球健康问题,受到生活方式和年龄的影响.
    • 有效的治疗方法存在,但生存高度依赖于阶段.
    • 广泛实施有组织的查计划对于减少CRC负担至关重要.