失眠症状与死亡率之间的关联:对美国男性的前性研究
Yanping Li1, Xuehong Zhang, John W Winkelman
1Channing Division of Network Medicine (Y.L., X.Z., F.B.H., M.S., J.M., X.G.) and Division of Sleep Medicine, Department of Medicine (J.W.W., S.R.), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Departments of Nutrition (F.B.H., M.S., X.G.) and Epidemiology (F.B.H., M.S.), Harvard School of Public Health, Boston, MA.
Circulation
|November 15, 2013
概括
失眠症状,如难以开始睡眠和非恢复性睡眠,与男性的死亡风险略有增加有关. 这项前性研究强调了持续睡眠障碍对健康的潜在影响.
科学领域:
- 老年学是指老年学的学科.
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 失眠在老年人中很普遍,可能与死亡风险相关,尽管现有证据不一致.
- 之前关于失眠和死亡率的研究产生了不同的结果,需要进一步调查.
研究的目的:
- 在一大批美国男性中,前性地调查失眠症状与死亡风险之间的关联.
- 为了确定特定的失眠症状,如难以启动或维持睡眠,预测死亡率增加.
主要方法:
- 一项前性队列研究,涉及23447名来自健康专业人员随访研究的美国男性,在基线没有癌症.
- 2004年收集了关于失眠症状的数据,并在2010年进行了跟踪,以确定2025例死亡.
- 根据年龄,生活方式因素和慢性疾病进行了多变量调整,以评估死亡风险.
主要成果:
- 难以开始睡眠与25%的总死亡风险增加有关 (HR,1.25;95% CI,1.04-1.50).
- 非恢复性睡眠与24%的总死亡风险增加有关 (HR,1.24;95% CI,1.05-1.46).
- 难以开始睡眠和非恢复性睡眠也与心血管疾病死亡风险增加有关.
结论:
- 某些失眠症状,特别是难以入睡和非恢复性睡眠,与死亡风险略高相关.
- 这些发现表明,特定的睡眠障碍与男性的长期健康结果之间存在联系.
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