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Updated: May 5, 2026

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
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肌肉线粒酶通过系统抑制胰岛素信号传递促进长寿

Edward Owusu-Ansah1, Wei Song, Norbert Perrimon

  • 1Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

Cell
|November 19, 2013
PubMed
概括

在Drosophila中轻度肌肉线粒体损伤通过激活补偿性应激反应来保持功能并延长寿命. 这涉及线粒体展开蛋白反应 (UPR) 和类似胰岛素的增长因子结合蛋白7,表明对衰老和代谢疾病的潜在治疗点.

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