通过通过组织过器触发近红外激发的氧化释放材料

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Peter T Burks1, John V Garcia, Ricardo GonzalezIrias

  • 1Department of Chemistry and Biochemistry, University of California, Santa Barbara , Santa Barbara, California 93106-9510, United States.

Journal of the American Chemical Society
|November 20, 2013
PubMed
概括

新的聚合物设备使用近红外光释放氧化 (NO). 这种方法可以在最小的组织损伤下进行有针对性的光疗,显示出对最小侵入性治疗的希望.

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Nitric oxide (NO), an inorganic gas, acts as a potent second messenger in most animal and plant tissues. NO diffuses out of the cells that produce it and enters the neighboring cells to generate a downstream response. NO synthase (NOS) catalyzes NO production by the deamination of the amino acid arginine. There are three isoforms of NOS. Endothelial cells have endothelial NOS (eNOS), nerve and muscle cells have neuronal NOS (nNOS), and macrophages produce inducible NOS (iNOS) upon exposure...
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