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肺动脉高血压中DNA损伤信号的作用

Jolyane Meloche1, Aude Pflieger, Mylène Vaillancourt

  • 1Department of Medicine, Laval University, Pulmonary Hypertension Research Group, IUCPQ Research Centre, Québec, Canada (J.M., A.P., M.V., F.P., C.G., A.C., S.B.-B., E.T., C.C., S.P., S.B.); and Vascular Biology Research Group, Department of Medicine, University of Alberta, Edmonton, Canada (R.P., S.Z., E.D.M.).

Circulation
|November 26, 2013
PubMed
概括

肺动脉高血压 (PAH) 涉及DNA损伤和炎症. 向多P-ribose) 聚合酶-1 (PARP-1) 在逆转PAH方面显示出前景,提供了一种新的治疗策略.

关键词:
造成的DNA损伤是DNA损伤.人类PARP1蛋白质,人类微RNAs 是一个微型RNA.肺动脉高血压 肺动脉高血压

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