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Updated: May 5, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
10:17

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

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遗传变异对发育过程中的基因表达动态的影响

Mirko Francesconi1, Ben Lehner2

  • 11] EMBL-CRG Systems Biology Unit, Centre for Genomic Regulation (CRG), Dr. Aiguader 88, 08003 Barcelona, Spain [2] Universitat Pompeu Fabra (UPF), Dr. Aiguader 88, 08003 Barcelona, Spain.

Nature
|November 26, 2013
PubMed
概括

遗传变异在发育过程中显著影响基因表达动态. 这项研究揭示了50%以上的cis表达定量特征位点 (eQTLs),并突出了遗传变异如何影响基因表达变化的时间和速率.

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