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脂酶D3基因中的罕见编码变异会导致阿尔茨海默病的风险

Carlos Cruchaga1,2, Celeste M Karch1,2, Sheng Chih Jin1

  • 1Department of Psychiatry, Washington University, St. Louis, MO, USA.

Nature
|December 17, 2013
PubMed
概括

在PLD3基因中的一种罕见变异显著增加了晚发性阿尔茨海默病 (LOAD) 的风险. 这一发现突显了PLD3在阿尔茨海默病病理学和APP处理中的作用.

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