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Updated: May 4, 2026

Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry
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Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry

Published on: March 18, 2012

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质子合电子转移和形配置对于C4a-hydroperoxyflavin形成和稳定在flavoenzyme中的重要

Thanyaporn Wongnate1, Panida Surawatanawong, Surawit Visitsatthawong

  • 1Department of Biochemistry and Center of Excellence in Protein Structure and Function, Faculty of Science, Mahidol University , Bangkok, 10400 Thailand.

Journal of the American Chemical Society
|December 26, 2013
PubMed
概括

这项研究揭示了二氧化酶 (P2O) 如何激活二氧化物. 一个关键的发现是,从His548的质子转移增强了二氧化物的激活,促进了催化作用的关键中间体的形成.

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