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Updated: May 3, 2026

Detection of Axonally Localized mRNAs in Brain Sections Using High-Resolution In Situ Hybridization
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在神经元中检测到单个β-actin mRNA,揭示了调节其可翻译性的机制

Adina R Buxbaum1, Bin Wu, Robert H Singer

  • 1Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

Science (New York, N.Y.)
|January 25, 2014
PubMed
概括

学习和记忆涉及突触变化. 这项研究揭示,大脑细胞在休眠状态下存储actin信使RNA (mRNA),该RNA通过神经元刺激来激活蛋白质合成.

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