Menachem Fromer1, Andrew J Pocklington2, David H Kavanagh2

  • 11] Division of Psychiatric Genomics in the Department of Psychiatry, and Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.

Nature
|January 28, 2014
PubMed
概括

影响 postsynaptic 蛋白质的基因的小 de novo 突变,如活性调节的细胞骨相关蛋白 (ARC) 和 N-甲基-d-酸盐受体 (NMDARs),与精神分裂症风险有关. 这些遗传发现揭示了与其他神经发育障碍共同的机制.

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