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在乳腺中的双能干细胞的现场鉴定

Anne C Rios1, Nai Yang Fu1, Geoffrey J Lindeman2

  • 11] Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia [2] Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3010, Australia [3].

Nature
|January 28, 2014
PubMed
概括

这项研究揭示了双能乳腺干细胞 (MaSCs) 和原始细胞驱动乳腺发育和恒温. 双重性MASCs对于成年乳腺维护和重塑至关重要.

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A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
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