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转录因子achaete-scute同类2启动毛囊T辅助细胞的发育

Xindong Liu1, Xin Chen2, Bo Zhong3

  • 11] Tsinghua University School of Medicine, Beijing 100084, China [2] Department of Immunology, MD Anderson Cancer Center, Houston, Texas 77054, USA.

Nature
|January 28, 2014
PubMed
概括

亚凯特-急性同类2 (Ascl2) 通过上调CXCR5,下调CCR7直接启动毛囊T辅助细胞 (TFH) 发育. 这种转录因子对于TFH细胞分化和生殖中心反应至关重要.

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