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S-adenosylmethionine脱碳酶1对肺血管重塑的影响

Friederike Christine Weisel1, Christina Kloepping, Alexandra Pichl

  • 1Excellence Cluster Cardio-Pulmonary System, Universities of Giessen and Marburg Lung Center, Member of the German Lung Center, Justus-Liebig-University Giessen, Giessen, Germany (F.C.W., C.K., A.P., A.S., B.K., J.W., M.R., H.A.G., F.G., W.S., R.T.S., N.W., G.K.); Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, IL (K.M.R.); Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan (K.I., K.N.); University of Hamburg, Pharmaceutical and Medicinal Chemistry, Hamburg, Germany (W.M., C.W.); Department of Cardiothoracic Surgery, University Hospital of Vienna, Vienna, Austria (W.K., P.J.); Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany (W.S.); and Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria (G.K.).

Circulation
|January 29, 2014
PubMed
概括

小鼠的肺高血压 (PH) 通过再氧化逆转,揭示了s-adenosylmethionine脱氧酶1 (AMD-1) 是一个关键的目标. 针对AMD-1显示出治疗PH的前景.

关键词:
细胞缺氧细胞缺氧.高血压,肺部高血压,肺部高血压.肌肉,光滑的,光滑的肌肉.

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