俄罗斯的酒精和死亡率:对151,000名成年人的前性观察研究
David Zaridze1, Sarah Lewington2, Alexander Boroda1
1Russian Cancer Research Centre, Moscow, Russia.
Lancet (London, England)
|February 4, 2014
概括
大量的伏特加消费显著增加了俄罗斯成年人过早死亡的风险. 这项前性研究证实了伏特加.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 酒精研究 酒精研究
背景情况:
- 俄罗斯成年人的过早死亡率异常高.
- 以前的回顾性研究将过度饮用伏特加与外部死亡原因和特定疾病联系起来.
- 这项研究旨在为这些协会提供前性证据.
研究的目的:
- 为了前性地研究伏特加消费与俄罗斯成年人死亡率之间的关联.
- 量化与不同水平的伏特加摄入量相关的过度死亡风险.
- 为了加强关于伏特加在过早死亡中的作用的现有证据.
主要方法:
- 这是一项前性队列研究,从1999年至2008年期间,俄罗斯三座城市的20万名成年人参与了该研究.
- 到2010年为151,000个人的特定死因随访.
- 对混因子进行调整的普森回归分析,以计算与伏特加消费相关的死亡相对风险.
主要成果:
- 在35-74岁的男性吸烟者中,每周更高的伏特加消费 (三瓶或更多) 与20年死亡风险显著增加有关 (35%在35-54岁,64%在55-74岁).
- 较重饮酒者的过度死亡率主要是由于先前研究中发现的外部原因和与酒精有关的疾病.
- 尽管自我报告饮酒的波动,基线伏特加消费强烈预测死亡风险.
结论:
- 这项大规模的前性研究提供了强有力的证据,表明伏特加消费是导致俄罗斯成年人过早死亡的高率的主要原因.
- 这些发现强调了重度饮酒对这一群体的公共卫生影响.
- 进一步的研究可能会探索减轻与酒精有关的伤害的干预措施.
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