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Updated: May 3, 2026

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一个激发性副腹腔核到AgRP神经元电路,驱动饥饿感

Michael J Krashes1, Bhavik P Shah1, Joseph C Madara2

  • 11] Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA [2] Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA (M.J.K.); National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224, USA (M.J.K.); Cardiovascular and Metabolic Diseases, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, USA (B.P.S.); Division of Pediatric Endocrinology, Departments of Pediatrics, University of Michigan, Ann Arbor, Michigan 48105, USA (D.P.O.); Cardiovascular and Metabolic Diseases, Novartis Institutes for BioMedical Research, 100 Technology Square, Cambridge, Massachusetts 02139, USA (L.V.). [3].

Nature
|February 4, 2014
PubMed
概括

研究人员发现了控制饥饿的新大脑路径. 下丘脑中的特定神经元,表达甲状腺释放激素 (TRH) 和垂体腺酸环酶激活多 (PACAP),激活阿古蒂相关 (AgRP) 神经元来驱动养行为.

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