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在早期核糖体组装过程中,蛋白引导RNA动态

Hajin Kim1, Sanjaya C Abeysirigunawarden2, Ke Chen3

  • 11] Department of Physics, Center for the Physics of Living Cells and Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA [2] Howard Hughes Medical Institute, Urbana, Illinois 61801, USA [3] [4] School of Nano-Bioscience and Chemical Engineering, Ulsan National Institute of Science and Technology, Ulsan 689-798, Republic of Korea (H.K.); Department of Biochemistry and Biophysics, University of California at San Francisco, 600 16th Street, San Francisco, California 94143-2200, USA (M.M.); Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, LHRRB-517, Boston, Massachusetts 02115-5730, USA (K.R.).

Nature
|February 14, 2014
PubMed
概括

早期结合蛋白,如核糖体蛋白S4,对于30S核糖体组装至关重要. 这项研究揭示了S4如何动态引导RNA结构,通过非原生中间体促进蛋白质添加.

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