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Updated: May 3, 2026

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GPR56的进化动态替代拼接调节了区域大脑皮层模式

Byoung-Il Bae1, Ian Tietjen, Kutay D Atabay

  • 1Division of Genetics and Genomics, Manton Center for Orphan Disease, and Howard Hughes Medical Institute, Boston Children's Hospital, Broad Institute of MIT and Harvard, and Departments of Pediatrics and Neurology, Harvard Medical School, Boston, MA 02115, USA.

Science (New York, N.Y.)
|February 18, 2014
PubMed
概括

一个GPR56基因调节元件的突变破坏了人类大脑的发育,特别影响了语言区域. 这一发现揭示了新皮层的进化和大脑形成中的基因调节.

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