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Updated: May 3, 2026

SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy
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SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy

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一个半拉链的SNARE复合体代表了膜融合中的功能中间体

Feng Li1, Daniel Kümmel, Jeff Coleman

  • 1Department of Cell Biology, School of Medicine, Yale University , 333 Cedar Street, New Haven, Connecticut 06520, United States.

Journal of the American Chemical Society
|February 19, 2014
PubMed
概括

可溶性N-乙基胺胺敏感因子附着蛋白受体 (SNARE) 蛋白通过两步路径调解膜融合. N-终端域组件是限制速度的,允许随后的C-终端拉链进行融合.

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