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Updated: May 2, 2026

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
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蛋白质激酶RIPK3的活性决定了细胞是否死于亡或亡

Kim Newton1, Debra L Dugger, Katherine E Wickliffe

  • 1Department of Physiological Chemistry, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.

Science (New York, N.Y.)
|February 22, 2014
PubMed
概括

受体相互作用蛋白激酶3 (RIPK3) 激酶活性对于亡至关重要. 不活跃的RIPK3意外触发了亡,而不活跃的RIPK1则阻止了亡,但允许其他细胞信号通路发挥作用.

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