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产生IL-35的B细胞是自身免疫和传染病期间免疫的关键调节者

Ping Shen1, Toralf Roch1, Vicky Lampropoulou1

  • 1Deutsches Rheuma-Forschungszentrum, a Leibniz Institute, Charitéplatz 1, 10117 Berlin, Germany.

Nature
|February 28, 2014
PubMed
概括

产生互白素-35 (IL-35) 的B细胞对于免疫调节至关重要. 它们的缺失会损害自身免疫性疾病的恢复,但会增强对细菌感染的抵抗力,揭示IL-35作为治疗点.

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