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Updated: May 2, 2026

Detection of a CDH1 Rare Transcript Variant in Fresh-frozen Gastric Cancer Tissues by Chip-based Digital PCR
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在纤维状肝细胞癌中检测出复发的DNAJB1-PRKACA化学转录

Joshua N Honeyman1, Elana P Simon, Nicolas Robine

  • 1Laboratory of Cellular Biophysics, Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

Science (New York, N.Y.)
|March 1, 2014
PubMed
概括

研究人员在100%的纤维状肝细胞癌 (FL-HCC) 病例中发现了一种新奇的嵌合体转录,DNAJB1-PRKACA. 这种基因变异是由于19号染色体的大量删除导致的,与罕见的肝癌的发展有关.

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Non-LTR Retrotransposons03:18

Non-LTR Retrotransposons

As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...
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