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Updated: May 2, 2026

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor LATS Biosensor
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河马信号调节微处理器,并将细胞密度依赖的miRNA生物发生与癌症联系起来

Masaki Mori1, Robinson Triboulet2, Morvarid Mohseni3

  • 1Stem Cell Program, Boston Children's Hospital, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Department of Biological Chemistry and Molecular Pharmacology and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Boston, MA 02115, USA.

Cell
|March 4, 2014
PubMed
概括

河马通路通过YAP调节来控制微RNA (miRNA) 的产生. 这种机制解释了细胞密度的变化如何影响miRNA水平,并可能导致癌症的发展.

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