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Updated: May 2, 2026

Method for the Isolation and Identification of mRNAs, microRNAs and Protein Components of Ribonucleoprotein Complexes from Cell Extracts using RIP-Chip
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Method for the Isolation and Identification of mRNAs, microRNAs and Protein Components of Ribonucleoprotein Complexes from Cell Extracts using RIP-Chip

Published on: September 29, 2012

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Dom34在3'未翻译区域中拯救了核糖体

Nicholas R Guydosh1, Rachel Green1

  • 1Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Cell
|March 4, 2014
PubMed
概括

蛋白Dom34在体内从截断的mRNA和非编码区域中拯救停滞的核糖体. 这一过程对于核糖体循环和维持细胞蛋白质合成平衡至关重要.

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Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
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