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快照:成人的海马体神经发生

Krishna C Vadodaria1, Fred H Gage1

  • 1Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

Cell
|March 4, 2014
PubMed
概括

No abstract available in PubMed .

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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