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Updated: May 2, 2026

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PINK1功能丧失突变通过NdufA10乌比基诺尼脱影响线粒体复合体I活动

Vanessa A Morais1, Dominik Haddad, Katleen Craessaerts

  • 1VIB Center for the Biology of Disease, 3000 Leuven, Belgium.

Science (New York, N.Y.)
|March 22, 2014
PubMed
概括

在帕金森病模型中,线粒体复合体I活动的丧失与减少NdufA10-250酸化有关. 恢复这种酸化可以挽救线粒体功能和突触缺陷,这表明PINK1相关的帕金森病的关键途径.

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