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在慢性压力过载期间,CD4+ T 细胞促进从增大到心力衰竭的过渡

Fanny Laroumanie1, Victorine Douin-Echinard1, Joffrey Pozzo1

  • 1From the Institut National de la Santé et de la Recherche Médicale UMR1048 (INSERM), Institute of Cardiovascular and Metabolic Diseases (I2MC), Rangueil, Toulouse, France (F.L., V.D.-E., C.V., F.T., M.D., A.P., N.P.); Toulouse III University, Toulouse, France (F.L., V.D.-E., C.V., F.T., M.D., A.P., N.P.); Department of Cardiology, University Hospital of Rangueil, Toulouse, France (J.P., O.L.); and INSERM-UMS 006-Microsurgery Facility, Toulouse, France (C.D., D.C.).

Circulation
|March 25, 2014
PubMed
概括

CD4(+) T细胞和特异性抗原识别对于补偿心脏缩到心力衰竭 (HF) 的进展至关重要. 阻断这些T细胞可以防止小鼠模型中HF的发展和不良的心脏重塑.

关键词:
心脏衰竭是因为心脏衰竭.淋巴细胞 淋巴细胞腹腔的重塑 腹腔的重塑

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