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Microfluidics in Assessing Platelet Function
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人类P2Y12受体与抗血栓药物复合的结构

Kaihua Zhang1, Jin Zhang1, Zhan-Guo Gao2

  • 11] CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China [2].

Nature
|March 28, 2014
PubMed
概括

研究人员确定了与AZD1283.3结合的P2Y12受体 (P2Y12R) 的晶体结构. 这揭示了独特的结构特征,并为开发用于抗血栓治疗的新型P2Y12R抑制剂提供了见解.

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