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Predictive Immune Modeling of Solid Tumors
Published on: February 25, 2020
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从子宫前到坟墓的个性化医疗
1The Scripps Translational Science Institute, The Scripps Research Institute and Scripps Health, La Jolla, CA 92037, USA.
Cell
|April 1, 2014
概括
每个个体在生物学上都是独一无二的,甚至是一卵双胞胎. 这是一个全面的综合.
科学领域:
- 基因组学和个性化医学
背景情况:
- 生物学上的独特性往往被低估,甚至在同卵双胞胎中也是如此.
- 奥米克技术的进步允许详细的个体生物概况.
研究的目的:
- 突出每个个体的深刻生物学独特性.
- 强调全面的OMIC数据在医疗保健中的潜力.
主要方法:
- 综合的奥米克评估,包括DNA/RNA测序.
- 蛋白质组,代谢组,微生物组,自身抗体和表观组的表征.
主要成果:
- 证明每个人都拥有独一无二的生物内容.
- 证实了超越像指纹这样的传统标记物的显著个体变异.
结论:
- 个性化生物数据为医疗治疗提供了前所未有的机会.
- 个性化数据可以推动新型预防性健康策略的开发.
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