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Updated: May 1, 2026

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定量蛋白质组学将NCOA4确定为载荷受体,可以调解铁类食

Joseph D Mancias1, Xiaoxu Wang2, Steven P Gygi3

  • 11] Division of Genomic Stability and DNA Repair, Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [2] Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Harvard Radiation Oncology Program, Boston, Massachusetts 02115, USA [4] Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.

Nature
|April 4, 2014
PubMed
概括

研究人员发现,核受体协活性剂4 (NCOA4) 作为一种特定类型的自性菌的选择性受体. 这一过程对于调节细胞内的铁含量至关重要.

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