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Assessing the Expression of Major Histocompatibility Complex Class I on Primary Murine Hippocampal Neurons by Flow Cytometry
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由MHC I类H2-Dbb共同调节的突触消除和学习规则

Hanmi Lee1, Barbara K Brott1, Lowry A Kirkby2

  • 1Departments of Biology and Neurobiology and Bio-X, James H. Clark Center, 318 Campus Drive, Stanford, California 94305, USA.

Nature
|April 4, 2014
PubMed
概括

主体组织相容性复合体 (MHC) 类I分子H2-D (b) 对于大脑中的突触消除至关重要. 这种分子通过平衡突触学习规则来调节精确的神经连接的形成,确保正确的脑部发育.

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