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Updated: Nov 7, 2025

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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在TCR和激动性-MHC之间积累的动态捕获键触发T细胞信号传递

Baoyu Liu1, Wei Chen1, Brian D Evavold2

  • 1Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.

Cell
|April 15, 2014
PubMed
概括

对T细胞受体 (TCR) 的机械力决定了适应性免疫. 强力延长激素TCR-pMHC键 (捕捉键) 和缩短对手键 (滑动键),通过反应影响T细胞信号传递.

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